Lee’s AI Neuromodulation Lab at Ewha

Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC10827640/ Abstract Purpose Treatment for epilepsy primarily involves antiseizure medications (ASMs), which can be characterized using the clinical data warehouse (CDW) database. In this study, we compared retention rates and time to successful treatment for various ASMs to reflect both efficacy and adverse effects in patients with newly-diagnosed epilepsy. Materials and Methods We identified newly-diagnosed epilepsy patients with

Link: https://pure.ewha.ac.kr/en/publications/clinical-outcomes-and-systemic-complications-related-to-severity-/ Abstract Background: Status epilepticus (SE) is a critical neurological emergency in patients with neurological and non-neurological diseases. Mortality rises with SE severity. However, whether brain injury or systemic organ dysfunction causes death after SE remains unclear. We studied clinical outcomes and systemic dysfunctions associated with SE using standardize

Link: https://pure.ewha.ac.kr/en/publications/how-does-the-brain-allow-the-eyes-to-see/ Abstract Did you know that it is not only your eyes that allow you to see? Your brain functions with the eyes to process and make sense of all things that you see. A part of the brain called the visual cortex is responsible for vision. The brain contains over 100 billion brain cells called neurons, and they work in “levels” to help you see the world—from a basic level in which you perceive

Link: https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/aelm.202300075 Abstract Real-time health monitoring technology in daily life requires mechanically robust and transparent electrodes for multimodal biosignal sensing from exposed human epidermis. Here, highly stretchable transparent electrodes comprising a water-dispersed conductive polymer, poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), and a protic ionic liquid (IL), 3-methylimidazolium:bi

Link: https://pmc.ncbi.nlm.nih.gov/articles/PMC10327932/ Abstract Stroke destroys neurons and their connections leading to focal neurological deficits. Although limited, many patients exhibit a certain degree of spontaneous functional recovery. Structural remodeling of the intracortical axonal connections is implicated in the reorganization of cortical motor representation maps, which is considered to be an underlying mechanism of the improvement in motor function. Therefore,

Link: https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2023.1059186/full Abstract Introduction Sleep is an essential function to sustain a healthy life, and sleep dysfunction can cause various physical and mental issues. In particular, obstructive sleep apnea (OSA) is one of the most common sleep disorders and, if not treated in a timely manner, OSA can lead to critical problems such as hypertension or heart disease. Methods The first crucial step in e

Link: https://academic.oup.com/sleep/article/46/6/zsad108/7123764 Abstract Study Objectives Evidence suggests that sleep–wake cycle disruption could be an early manifestation of neurodegeneration and might even be a risk factor for developing diseases in healthy adults. We investigated the impact of circadian phase change on structural and functional brain deterioration in a late-adulthood population. Methods We analyzed the data of 1874 participants (mean age 58.6 ± 6.3 year

Link: https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.1159227/full Abstract Impaired airway clearance in patients with non-cystic fibrosis bronchiectasis causes frequent bacterial infection, chronic inflammation, and progressive tissue destruction. We aimed to evaluate whether an oscillating positive expiratory pressure (OPEP) device could allow effective sputum expectoration and prevent acute exacerbations in patients with bronchiectasis who had freq

Link: https://www.mdpi.com/2072-6643/15/6/1309 Abstract Dried Chrysanthemum morifolium (Chry) flowers have been used in Korea as a traditional insomnia treatment. In this study, the sleep-promoting activity and improving sleep quality of Chry extract (ext) and its active substance linarin were analyzed by pentobarbital-induced sleep experiment in mice and electroencephalography (EEG), electromyogram (EMG) analysis in rats. In a dose-dependent manner, Chry ext and linarin prom

Link: https://pure.ewha.ac.kr/en/publications/eeg-feature-engineering-for-machine-learning-based-cpap-titration/ Abstract Obstructive sleep apnea (OSA) is one of the most prevalent sleep disorders that can lead to serious consequences, including hypertension and/or cardiovascular diseases, if not treated promptly. Continuous positive airway pressure (CPAP) is widely recognized as the most effective treatment for OSA, which needs the proper titration of airway pressure to achi